… Pediatric acute myeloid leukemia with t(8;16)(p11;p13), a distinct clinical and biological entity:
a collaborative study by the InternationalBerlin-Frankfurt-Munster AML-study group. Blood. …

… different systems exist for subclassification of acute myeloid … 2 Studies on clinical
characteristics and outcome in pediatric … A total of 159 cases of AML carrying the t(8;16)(p11;p13) …

… (AML) is a rare subgroup of AML of pediatric patients under … in AML associated with t(8;16)(p11;p13)
[15,16]. These … Some collaborative groups have defined AML<1 year old as a …

… with distinct clinical and morphologic features and poor prognosis. AML with t(8;16) translocation
can occur in adults or children. … cooperative mutations are common in AML with t(8;16) …

… CBF AML study [89], confirming the previous results in inv(16) … a relatively biological and
clinical homogeneous group with a … The translocation t(8;16)(p11;p13) is a rare entity leading to …

… the I-BFM-AML Study Group , Hypodiploidy has unfavorable impact … from the International
Berlin-Frankfurt-Münster (I-BFM) … ;16)(p13;q22), data regarding high-risk features for pediatric …

… ,17], and pediatric patients tend to be de novo [13]. There are … clinical features that mimic
acute promyelocytic leukemia (… often show unique clinical and biological characteristics [22]. …

… /infant leukemia accounts for <1% of all childhood leukemias. When … study groups (International
Berlin-Frankfurt-Münster … , characteristic for infant AML, are t(1;22)(p13.3;q13.1)/RBM15-…

… driving current therapies and upcoming clinical trials. … Similarly, myeloid leukemia of Down's
syndrome is a unique … Thus, pediatric cooperative groups remain divided on cytarabine …

… AML without known type 2 aberrations using routine clinical diagnostics, which varied
among the participating collaborative groups in this study as they all used a slightly different …